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Dwairy, M.D., is a Houston-born gastroenterologist at Houston Regional Gastroenterology Institute, treating patients in Sugar Land and Humble with expertise shaped by extensive training at UT Houston

Latest perspectives on alzheimers disease treatment: the role of blood-brain barrier and antioxidant-based drug delivery systems

Hyperglycemia, AGEs, mitochondrial oxidative stress and ultrafiltration cytokines act on renal tubular cells and trigger multiple cellular pathways such as PKC-, -, and -, NF-B, P38 and ERK1/2 pathways, further exacerbating renal tubular cell hypertrophy, apoptosis, and accumulation of tubulointerstitial inflammatory factors (3)

10.1002/ame2.12262 [DOI] [PMC free article] [PubMed] [Google Scholar] 23.Chu J, Feng S, Guo C, Xue B, He K, Li L