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Despite their established role in promoting weight loss, there is a paucity of research investigating the safety or efficacy of GLP-1RAs in people whose eating disorders have a psychopathological component (for example, anorexia nervosa, bulimia nervosa) as conventionally defined by diagnostic manuals

To examine whether the decreased FASN levels could result from NOTCH inhibition, we assessed the level of Notch signaling by identifying the levels of NOTCH1, NOTCH2, and their most direct downstream effector, HES1 (43), in GSH-depleted livers

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