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Thorough programs include baseline laboratory testing (IGF-1, thorough metabolic panel, lipid profile), 3-month follow-up labs, and regular clinical assessments
Where it works: Adipose tissue (fat cells): Reduces inflammation and may improve fat metabolism Pancreas: Works alongside GLP-1 to enhance insulin secretion Brain: May contribute to appetite regulation (research ongoing) Weight loss contribution: When GIP is added to GLP-1 (as in tirzepatide), weight loss increases from ~15% to ~22%
Dosing Considerations The recommended dose-escalation time period for GLP-1 RA is intended to improve GI tolerability to AEs such as nausea, vomiting and diarrhoea, which are common when initiating GLP-1 RAs [16, 18, 20, 22, 24, 26, 28]