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Researchers observed quick changes in inflammatory signaling and cellular metabolism within cartilage tissue , suggesting that chondrocytes may function differently when the systemic metabolic environment changes

doi: 10.3389/fphar.2024.1347047 Received 06 December 2023 Accepted 15 March 2024 Published 28 March 2024 Volume 15 - 2024 Edited by Chenghai Liu, Shanghai University of Traditional Chinese Medicine, China Reviewed by Fu-Shun Yen, Dr

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While this review does not aim to be exhaustive, we propose an integrative framework that redefines glial stress responses through the combined lenses of inflammation, transcriptomics, mitochondrial dynamics, lipid metabolism, epigenomic regulation, and cellular senescence