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It mimics a natural hormone released after eating, which signals fullness to your brain

The anorexic action of these hormones is thought at least in part to be mediated through activation of their cognate G-protein coupled receptors (GLP1R and NPY2R, respectively) located on vagal afferent nerve terminals, originating from neurons with somata in the nodose ganglia 2

TRIUMPH-2 studies obesity in adults with type 2 diabetes

According to a 2017 study by Martinak et al., published in Psychopharmacology Bulletin , dextromethorphan abuse results in significant psychiatric symptoms, highlighting its potential for misuse