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Individuals with certain medical conditions or who take certain medications should consult with a healthcare provider prior to initiating

Clinical trials show tirzepatide-treated patients lose up to 22.5% of body weight over 68 weeks, compared to semaglutide's 17.4% in similar populations

Secondly, if we were to not assign reweighting to those MIPS eligible clinicians, many of them would receive a very low final score because they did not submit data for one or more performance categories during the year in which they received reweighting

When the body loses weight quickly, several metabolic changes occur that predispose to gallstone development: Increased cholesterol secretion into bile as the body mobilises fat stores Reduced gallbladder motility and emptying, leading to bile stasis Altered bile composition , with a higher ratio of cholesterol to bile salts Decreased gallbladder contractility , partly due to reduced food intake and prolonged fasting periods Very rapid weight loss, such as that following bariatric surgery, has been associated with gallstone formation in approximately 10-25% of patients