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They should understand that semaglutide is typically a long-term therapy, and discontinuation may result in weight regain

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Correspondingly, fat mass loss comprised a larger proportion of total weight loss among those who received apitegromab (85.3% of total loss (81.289.5%) or 8.5 kg (7.49.6)) compared to those who received placebo (69.5% (65.773.3%) or 8.0 kg (7.09.0))

When taken together, these effects may become more pronounced